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IFIT1 Differentially Interferes with Translation and Replication of Alphavirus Genomes and Promotes Induction of Type I Interferon

Alphaviruses are a group of widely distributed human and animal pathogens. It is well established that their replication is sensitive to type I IFN treatment, but the mechanism of IFN inhibitory function remains poorly understood. Using a new experimental system, we demonstrate that in the presence...

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Detalles Bibliográficos
Autores principales:	Reynaud, Josephine M., Kim, Dal Young, Atasheva, Svetlana, Rasalouskaya, Aliaksandra, White, James P., Diamond, Michael S., Weaver, Scott C., Frolova, Elena I., Frolov, Ilya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415776/ https://www.ncbi.nlm.nih.gov/pubmed/25927359 http://dx.doi.org/10.1371/journal.ppat.1004863

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