Native Variants of the MRB1 Complex Exhibit Specialized Functions in Kinetoplastid RNA Editing

Adaptation and survival of Trypanosoma brucei requires editing of mitochondrial mRNA by uridylate (U) insertion and deletion. Hundreds of small guide RNAs (gRNAs) direct the mRNA editing at over 3,000 sites. RNA editing is controlled during the life cycle but the regulation of substrate and stage sp...

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Detalles Bibliográficos
Autores principales: Madina, Bhaskara R., Kumar, Vikas, Mooers, Blaine H. M., Cruz-Reyes, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415780/
https://www.ncbi.nlm.nih.gov/pubmed/25928631
http://dx.doi.org/10.1371/journal.pone.0123441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415780/
https://www.ncbi.nlm.nih.gov/pubmed/25928631
http://dx.doi.org/10.1371/journal.pone.0123441

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