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Native Variants of the MRB1 Complex Exhibit Specialized Functions in Kinetoplastid RNA Editing
Adaptation and survival of Trypanosoma brucei requires editing of mitochondrial mRNA by uridylate (U) insertion and deletion. Hundreds of small guide RNAs (gRNAs) direct the mRNA editing at over 3,000 sites. RNA editing is controlled during the life cycle but the regulation of substrate and stage sp...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415780/ https://www.ncbi.nlm.nih.gov/pubmed/25928631 http://dx.doi.org/10.1371/journal.pone.0123441 |