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IDOL N342S Variant, Atherosclerosis Progression and Cardiovascular Disorders in the Italian General Population

Inducible degrader of the low density lipoprotein receptor (IDOL), is an E3 ubiquitin ligase that negatively modulates low density lipoprotein receptor (LDL-R) expression. Genome-wide association studies (GWAS) indicated that genetic variants in IDOL gene contributes to variation in LDL-C plasma lev...

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Detalles Bibliográficos
Autores principales: Dhyani, Ashish, Tibolla, Gianpaolo, Baragetti, Andrea, Garlaschelli, Katia, Pellegatta, Fabio, Grigore, Liliana, Norata, Giuseppe Danilo, Catapano, Alberico Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415795/
https://www.ncbi.nlm.nih.gov/pubmed/25927920
http://dx.doi.org/10.1371/journal.pone.0122414