Granzyme A Is Required for Regulatory T-Cell Mediated Prevention of Gastrointestinal Graft-versus-Host Disease

In our previous work we could identify defects in human regulatory T cells (Tregs) likely favoring the development of graft-versus-host disease (GvHD) following allogeneic stem cell transplantation (SCT). Treg transcriptome analyses comparing GvHD and immune tolerant patients uncovered regulated gen...

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Detalles Bibliográficos
Autores principales: Velaga, Sarvari, Ukena, Sya N., Dringenberg, Ulrike, Alter, Christina, Pardo, Julian, Kershaw, Olivia, Franzke, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415808/
https://www.ncbi.nlm.nih.gov/pubmed/25928296
http://dx.doi.org/10.1371/journal.pone.0124927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415808/
https://www.ncbi.nlm.nih.gov/pubmed/25928296
http://dx.doi.org/10.1371/journal.pone.0124927

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