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Influence of Spironolactone on Matrix Metalloproteinase-2 in Acute Decompensated Heart Failure

BACKGROUND: Matrix metalloproteinases (MMPs) are a family of enzymes important for the resorption of extracellular matrices, control of vascular remodeling and repair. Increased activity of MMP2 has been demonstrated in heart failure, and in acutely decompensated heart failure (ADHF) a decrease in c...

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Detalles Bibliográficos
Autores principales: Ferreira, João Pedro, Santos, Mário, Oliveira, José Carlos, Marques, Irene, Bettencourt, Paulo, Carvalho, Henrique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cardiologia 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415867/
https://www.ncbi.nlm.nih.gov/pubmed/25993594
http://dx.doi.org/10.5935/abc.20140205