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Influence of Spironolactone on Matrix Metalloproteinase-2 in Acute Decompensated Heart Failure
BACKGROUND: Matrix metalloproteinases (MMPs) are a family of enzymes important for the resorption of extracellular matrices, control of vascular remodeling and repair. Increased activity of MMP2 has been demonstrated in heart failure, and in acutely decompensated heart failure (ADHF) a decrease in c...
Autores principales: | Ferreira, João Pedro, Santos, Mário, Oliveira, José Carlos, Marques, Irene, Bettencourt, Paulo, Carvalho, Henrique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Cardiologia
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415867/ https://www.ncbi.nlm.nih.gov/pubmed/25993594 http://dx.doi.org/10.5935/abc.20140205 |
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