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Ascl1 phospho-status regulates neuronal differentiation in a Xenopus developmental model of neuroblastoma

Neuroblastoma (NB), although rare, accounts for 15% of all paediatric cancer mortality. Unusual among cancers, NBs lack a consistent set of gene mutations and, excluding large-scale chromosomal rearrangements, the genome seems to be largely intact. Indeed, many interesting features of NB suggest tha...

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Detalles Bibliográficos
Autores principales: Wylie, Luke A., Hardwick, Laura J. A., Papkovskaia, Tatiana D., Thiele, Carol J., Philpott, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415893/
https://www.ncbi.nlm.nih.gov/pubmed/25786414
http://dx.doi.org/10.1242/dmm.018630