Neurodegeneration severity can be predicted from early microglia alterations monitored in vivo in a mouse model of chronic glaucoma

Microglia serve key homeostatic roles, and respond to neuronal perturbation and decline with a high spatiotemporal resolution. The course of all chronic CNS pathologies is thus paralleled by local microgliosis and microglia activation, which begin at early stages of the disease. However, the possibi...

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Detalles Bibliográficos
Autores principales: Bosco, Alejandra, Romero, Cesar O., Breen, Kevin T., Chagovetz, Alexis A., Steele, Michael R., Ambati, Balamurali K., Vetter, Monica L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415894/
https://www.ncbi.nlm.nih.gov/pubmed/25755083
http://dx.doi.org/10.1242/dmm.018788

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415894/
https://www.ncbi.nlm.nih.gov/pubmed/25755083
http://dx.doi.org/10.1242/dmm.018788

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