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Sodium Thiosulfate Ameliorates Oxidative Stress and Preserves Renal Function in Hyperoxaluric Rats

BACKGROUND: Hyperoxaluria causes crystal deposition in the kidney, which leads to oxidative stress and to injury and damage of the renal epithelium. Sodium thiosulfate (STS, Na(2)S(2)O(3)) is an anti-oxidant, which has been used in human medicine for decades. The effect of STS on hyperoxaluria-induc...

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Detalles Bibliográficos
Autores principales: Bijarnia, Rakesh K., Bachtler, Matthias, Chandak, Prakash G., van Goor, Harry, Pasch, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415920/
https://www.ncbi.nlm.nih.gov/pubmed/25928142
http://dx.doi.org/10.1371/journal.pone.0124881