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Antimetastatic Therapies of the Polysulfide Diallyl Trisulfide against Triple-Negative Breast Cancer (TNBC) via Suppressing MMP2/9 by Blocking NF-κB and ERK/MAPK Signaling Pathways

BACKGROUND: Migration and invasion are two crucial steps of tumor metastasis. Blockage of these steps may be an effective strategy to reduce the risk. The objective of the present study was to investigate the effects of diallyl trisulfide (DATS), a natural organosulfuric compound with most sulfur at...

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Detalles Bibliográficos
Autores principales: Liu, Yuping, Zhu, Pingting, Wang, Yingyu, Wei, Zhonghong, Tao, Li, Zhu, Zhijie, Sheng, Xiaobo, Wang, Siliang, Ruan, Junshan, Liu, Zhaoguo, Cao, Yuzhu, Shan, Yunlong, Sun, Lihua, Wang, Aiyun, Chen, Wenxing, Lu, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415928/
https://www.ncbi.nlm.nih.gov/pubmed/25927362
http://dx.doi.org/10.1371/journal.pone.0123781