Modulation of Bleomycin-Induced Lung Fibrosis by Pegylated Hyaluronidase and Dopamine Receptor Antagonist in Mice

Hyaluronidases are groups of enzymes that degrade hyaluronic acid (HA). To stop enzymatic hydrolysis we modified testicular hyaluronidase (HYAL) by activated polyethylene oxide with the help of electron-beam synthesis. As a result we received pegylated hyaluronidase (pegHYAL). Spiperone is a selecti...

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Detalles Bibliográficos
Autores principales: Skurikhin, Evgenii Germanovich, Pershina, Olga Victorovna, Reztsova, Alena Mikhaylovna, Ermakova, Natalia Nikolaevna, Khmelevskaya, Ekaterina Sergeevna, Krupin, Vycheslav Andreevich, Stepanova, Inna Ernestovna, Artamonov, Andrew Vladimirovich, Bekarev, Andrew Alexandrovich, Madonov, Pavel Gennadjevich, Dygai, Alexander Mikhaylovich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415936/
https://www.ncbi.nlm.nih.gov/pubmed/25927611
http://dx.doi.org/10.1371/journal.pone.0125065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415936/
https://www.ncbi.nlm.nih.gov/pubmed/25927611
http://dx.doi.org/10.1371/journal.pone.0125065

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