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Neonatal Isoflurane Exposure Induces Neurocognitive Impairment and Abnormal Hippocampal Histone Acetylation in Mice

BACKGROUND: Neonatal exposure to isoflurane may induce long-term memory impairment in mice. Histone acetylation is an important form of chromatin modification that regulates the transcription of genes required for memory formation. This study investigated whether neonatal isoflurane exposure-induced...

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Detalles Bibliográficos
Autores principales: Zhong, Tao, Guo, Qulian, Zou, Wangyuan, Zhu, Xiaoyan, Song, Zongbin, Sun, Bei, He, Xin, Yang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415954/
https://www.ncbi.nlm.nih.gov/pubmed/25928815
http://dx.doi.org/10.1371/journal.pone.0125815