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Neonatal Isoflurane Exposure Induces Neurocognitive Impairment and Abnormal Hippocampal Histone Acetylation in Mice
BACKGROUND: Neonatal exposure to isoflurane may induce long-term memory impairment in mice. Histone acetylation is an important form of chromatin modification that regulates the transcription of genes required for memory formation. This study investigated whether neonatal isoflurane exposure-induced...
Autores principales: | Zhong, Tao, Guo, Qulian, Zou, Wangyuan, Zhu, Xiaoyan, Song, Zongbin, Sun, Bei, He, Xin, Yang, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415954/ https://www.ncbi.nlm.nih.gov/pubmed/25928815 http://dx.doi.org/10.1371/journal.pone.0125815 |
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