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The Nitric Oxide Donor Pentaerythritol Tetranitrate Reduces Platelet Activation in Congestive Heart Failure

BACKGROUND: Platelet activation associated with endothelial dysfunction and impaired endogenous platelet inhibition is part of the cardiovascular phenotype of congestive heart failure (CHF) and contributes to the increased risk for thromboembolic complications. Pentaerythritol tetranitrate (PETN) ha...

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Detalles Bibliográficos
Autores principales: Flierl, Ulrike, Fraccarollo, Daniela, Widder, Julian D., Micka, Jan, Neuser, Jonas, Bauersachs, Johann, Schäfer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415973/
https://www.ncbi.nlm.nih.gov/pubmed/25928879
http://dx.doi.org/10.1371/journal.pone.0123621