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A Two-Gene Blood Test for Methylated DNA Sensitive for Colorectal Cancer

BACKGROUND: Specific genes are methylated with high frequency in colorectal neoplasia, and may leak into blood. Detection of multiple methylated DNA biomarkers in blood may improve assay sensitivity for colorectal cancer (CRC) relative to a single marker. We undertook a case-control study evaluating...

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Detalles Bibliográficos
Autores principales: Pedersen, Susanne K., Baker, Rohan T., McEvoy, Aidan, Murray, David H., Thomas, Melissa, Molloy, Peter L., Mitchell, Sue, Lockett, Trevor, Young, Graeme P., LaPointe, Lawrence C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416022/
https://www.ncbi.nlm.nih.gov/pubmed/25928810
http://dx.doi.org/10.1371/journal.pone.0125041