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5Z-7-Oxozeanol Inhibits the Effects of TGFβ1 on Human Gingival Fibroblasts

Transforming growth factor (TGF)β acts on fibroblasts to promote the production and remodeling of extracellular matrix (ECM). In adult humans, excessive action of TGFβ is associated with fibrotic disease and fibroproliferative conditions, including gingival hyperplasia. Understanding how the TGFβ1 s...

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Detalles Bibliográficos
Autores principales: Kuk, Hanna, Hutchenreuther, James, Murphy-Marshman, Hannah, Carter, David, Leask, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416036/
https://www.ncbi.nlm.nih.gov/pubmed/25927238
http://dx.doi.org/10.1371/journal.pone.0123689