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5Z-7-Oxozeanol Inhibits the Effects of TGFβ1 on Human Gingival Fibroblasts
Transforming growth factor (TGF)β acts on fibroblasts to promote the production and remodeling of extracellular matrix (ECM). In adult humans, excessive action of TGFβ is associated with fibrotic disease and fibroproliferative conditions, including gingival hyperplasia. Understanding how the TGFβ1 s...
Autores principales: | Kuk, Hanna, Hutchenreuther, James, Murphy-Marshman, Hannah, Carter, David, Leask, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416036/ https://www.ncbi.nlm.nih.gov/pubmed/25927238 http://dx.doi.org/10.1371/journal.pone.0123689 |
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