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Elevation of Soluble Guanylate Cyclase Suppresses Proliferation and Survival of Human Breast Cancer Cells

Nitric oxide (NO) is an essential signaling molecule in biological systems. Soluble guanylate cyclase (sGC), composing of α1 and β1 subunit, is the receptor for NO. Using radioimmunoassay, we discovered that activation of sGC by treatment with bradykinin or sodium nitroprusside (SNP) is impaired in...

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Detalles Bibliográficos
Autores principales: Wen, Hui-Chin, Chuu, Chih-Pin, Chen, Chen-Yu, Shiah, Shine-Gwo, Kung, Hsing-Jien, King, Kuang-Liang, Su, Liang-Chen, Chang, Shi-Chuan, Chang, Chung-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416047/
https://www.ncbi.nlm.nih.gov/pubmed/25928539
http://dx.doi.org/10.1371/journal.pone.0125518