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A structure-based Multiple-Instance Learning approach to predicting in vitro transcription factor-DNA interaction

BACKGROUND: Understanding the mechanism of transcriptional regulation remains an inspiring stage of molecular biology. Recently, in vitro protein-binding microarray experiments have greatly improved the understanding of transcription factor-DNA interaction. We present a method - MIL3D - which predic...

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Detalles Bibliográficos
Autores principales: Gao, Zhen, Ruan, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416172/
https://www.ncbi.nlm.nih.gov/pubmed/25917392
http://dx.doi.org/10.1186/1471-2164-16-S4-S3