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Parameter optimization for constructing competing endogenous RNA regulatory network in glioblastoma multiforme and other cancers

BACKGROUND: In addition to direct targeting and repressing mRNAs, recent studies reported that microRNAs (miRNAs) can bridge up an alternative layer of post-transcriptional gene regulatory networks. The competing endogenous RNA (ceRNA) regulation depicts the scenario where pairs of genes (ceRNAs) sh...

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Detalles Bibliográficos
Autores principales: Chiu, Yu-Chiao, Hsiao, Tzu-Hung, Chen, Yidong, Chuang, Eric Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416191/
https://www.ncbi.nlm.nih.gov/pubmed/25917195
http://dx.doi.org/10.1186/1471-2164-16-S4-S1