Selective inhibition of liver X receptor α-mediated lipogenesis in primary hepatocytes by licochalcone A

BACKGROUND: Sterol regulatory element binding protein-1c (SREBP-1c) is a regulator of the lipogenic pathway and is transcriptionally activated by liver X receptor α (LXRα). This study aims to investigate phytochemicals inhibiting the autonomous transactivity of LXRα with potentials as SREBP-1c inhib...

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Detalles Bibliográficos
Autores principales: Oh, Gyun-Sik, Lee, Gang Gu, Yoon, Jin, Oh, Won Keun, Kim, Seung-Whan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416341/
https://www.ncbi.nlm.nih.gov/pubmed/25937827
http://dx.doi.org/10.1186/s13020-015-0037-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416341/
https://www.ncbi.nlm.nih.gov/pubmed/25937827
http://dx.doi.org/10.1186/s13020-015-0037-x

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