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Selective inhibition of liver X receptor α-mediated lipogenesis in primary hepatocytes by licochalcone A
BACKGROUND: Sterol regulatory element binding protein-1c (SREBP-1c) is a regulator of the lipogenic pathway and is transcriptionally activated by liver X receptor α (LXRα). This study aims to investigate phytochemicals inhibiting the autonomous transactivity of LXRα with potentials as SREBP-1c inhib...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416341/ https://www.ncbi.nlm.nih.gov/pubmed/25937827 http://dx.doi.org/10.1186/s13020-015-0037-x |