Monoacylglycerol lipase inhibitor JZL184 reduces neuroinflammatory response in APdE9 mice and in adult mouse glial cells

BACKGROUND: Recently, the role of monoacylglycerol lipase (MAGL) as the principal regulator of simultaneous prostaglandin synthesis and endocannabinoid receptor activation in the CNS was demonstrated. To expand upon previously published research in the field, we observed the effect of the MAGL inhib...

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Detalles Bibliográficos
Autores principales: Pihlaja, Rea, Takkinen, Jatta, Eskola, Olli, Vasara, Jenni, López-Picón, Francisco R, Haaparanta-Solin, Merja, Rinne, Juha O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416350/
https://www.ncbi.nlm.nih.gov/pubmed/25927213
http://dx.doi.org/10.1186/s12974-015-0305-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416350/
https://www.ncbi.nlm.nih.gov/pubmed/25927213
http://dx.doi.org/10.1186/s12974-015-0305-9

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