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Plasma and urine metabolic profiles are reflective of altered beta-oxidation in non-diabetic obese subjects and patients with type 2 diabetes mellitus

OBJECTIVES: The two primary pathophysiological characteristics of patients with type 2 diabetes mellitus (T2DM) are insulin resistance (IR) and beta cell dysfunction. It has been proposed that the development of IR is secondary to the accumulation of triacylglycerols and fatty acids in the muscle an...

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Detalles Bibliográficos
Autores principales: Villarreal-Pérez, Jesús Zacarías, Villarreal-Martínez, Jesús Zacarías, Lavalle-González, Fernando Javier, Torres-Sepúlveda, María del Rosario, Ruiz-Herrera, Consuelo, Cerda-Flores, Ricardo Martín, Castillo-García, Erik Rubén, Rodríguez-Sánchez, Irám Pablo, Martínez de Villarreal, Laura Elia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416397/
https://www.ncbi.nlm.nih.gov/pubmed/25937838
http://dx.doi.org/10.1186/1758-5996-6-129