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Hippocampal glutamate-glutamine (Glx) in adults with Down syndrome: a preliminary study using in vivo proton magnetic resonance spectroscopy ((1)H MRS)

BACKGROUND: Down syndrome (DS), or trisomy 21, is one of the most common autosomal mutations. People with DS have intellectual disability (ID) and are at significantly increased risk of developing Alzheimer’s disease (AD). The biological associates of both ID and AD in DS are poorly understood, but...

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Detalles Bibliográficos
Autores principales: Tan, Giles MY, Beacher, Felix, Daly, Eileen, Horder, Jamie, Prasher, Verinder, Hanney, Maria-Luisa, Morris, Robin, Lovestone, Simon, Murphy, Kieran C, Simmons, Andrew, Murphy, Declan GM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416419/
https://www.ncbi.nlm.nih.gov/pubmed/25937842
http://dx.doi.org/10.1186/1866-1955-6-42