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The study of homology between tumor progression genes and members of retroviridae as a tool to predict target-directed therapy failure

Oncogenes are the primary candidates for target-directed therapy, given that they are involved directly in the progression and resistance of tumors. However, the appearance of point mutations can hinder the treatment of patients with these new molecules, raising costs and the need to development new...

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Detalles Bibliográficos
Autor principal: Fernandes, Janaina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416442/
https://www.ncbi.nlm.nih.gov/pubmed/25983693
http://dx.doi.org/10.3389/fphar.2015.00092