Enzymatic C(sp(3))-H Amination: P450-Catalyzed Conversion of Carbonazidates into Oxazolidinones

[Image: see text] Cytochrome P450 enzymes can effectively promote the activation and cyclization of carbonazidate substrates to yield oxazolidinones via an intramolecular nitrene C–H insertion reaction. Investigation of the substrate scope shows that while benzylic/allylic C–H bonds are most readily...

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Detalles Bibliográficos
Autores principales: Singh, Ritesh, Kolev, Joshua N., Sutera, Philip A., Fasan, Rudi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416466/
https://www.ncbi.nlm.nih.gov/pubmed/25954592
http://dx.doi.org/10.1021/cs5018612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416466/
https://www.ncbi.nlm.nih.gov/pubmed/25954592
http://dx.doi.org/10.1021/cs5018612

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