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A Weighted Polygenic Risk Score Using 14 Known Susceptibility Variants to Estimate Risk and Age Onset of Psoriasis in Han Chinese

With numbers of common variants identified mainly through genome-wide association studies (GWASs), there is great interest in incorporating the findings into screening individuals at high risk of psoriasis. The purpose of this study is to establish genetic prediction models and evaluate its discrimi...

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Detalles Bibliográficos
Autores principales: Yin, Xianyong, Cheng, Hui, Lin, Yan, Wineinger, Nathan E., Zhou, Fusheng, Sheng, Yujun, Yang, Chao, Li, Pan, Li, Feng, Shen, Changbing, Yang, Sen, Schork, Nicholas J., Zhang, Xuejun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416725/
https://www.ncbi.nlm.nih.gov/pubmed/25933357
http://dx.doi.org/10.1371/journal.pone.0125369