Effects of Tramadol on Substantia Gelatinosa Neurons in the Rat Spinal Cord: An In Vivo Patch-Clamp Analysis

Tramadol is thought to modulate synaptic transmissions in the spinal dorsal horn mainly by activating µ-opioid receptors and by inhibiting the reuptake of monoamines in the CNS. However, the precise mode of modulation remains unclear. We used an in vivo patch clamp technique in urethane-anesthetized...

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Detalles Bibliográficos
Autores principales: Yamasaki, Hiroyuki, Funai, Yusuke, Funao, Tomoharu, Mori, Takashi, Nishikawa, Kiyonobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416729/
https://www.ncbi.nlm.nih.gov/pubmed/25933213
http://dx.doi.org/10.1371/journal.pone.0125147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416729/
https://www.ncbi.nlm.nih.gov/pubmed/25933213
http://dx.doi.org/10.1371/journal.pone.0125147

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