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Factor H–Related Protein 5 Interacts with Pentraxin 3 and the Extracellular Matrix and Modulates Complement Activation

The physiological roles of the factor H (FH)-related proteins are controversial and poorly understood. Based on genetic studies, FH-related protein 5 (CFHR5) is implicated in glomerular diseases, such as atypical hemolytic uremic syndrome, dense deposit disease, and CFHR5 nephropathy. CFHR5 was also...

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Detalles Bibliográficos
Autores principales: Csincsi, Ádám I., Kopp, Anne, Zöldi, Miklós, Bánlaki, Zsófia, Uzonyi, Barbara, Hebecker, Mario, Caesar, Joseph J. E., Pickering, Matthew C., Daigo, Kenji, Hamakubo, Takao, Lea, Susan M., Goicoechea de Jorge, Elena, Józsi, Mihály
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416742/
https://www.ncbi.nlm.nih.gov/pubmed/25855355
http://dx.doi.org/10.4049/jimmunol.1403121