Prognostic Impact of Reduced Connexin43 Expression and Gap Junction Coupling of Neoplastic Stromal Cells in Giant Cell Tumor of Bone

Missense mutations of the GJA1 gene encoding the gap junction channel protein connexin43 (Cx43) cause bone malformations resulting in oculodentodigital dysplasia (ODDD), while GJA1 null and ODDD mutant mice develop osteopenia. In this study we investigated Cx43 expression and channel functions in gi...

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Detalles Bibliográficos
Autores principales: Balla, Peter, Maros, Mate Elod, Barna, Gabor, Antal, Imre, Papp, Gergo, Sapi, Zoltan, Athanasou, Nicholas Anthony, Benassi, Maria Serena, Picci, Pierro, Krenacs, Tibor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416750/
https://www.ncbi.nlm.nih.gov/pubmed/25933380
http://dx.doi.org/10.1371/journal.pone.0125316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416750/
https://www.ncbi.nlm.nih.gov/pubmed/25933380
http://dx.doi.org/10.1371/journal.pone.0125316

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