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A 1-Cys Peroxiredoxin from a Thermophilic Archaeon Moonlights as a Molecular Chaperone to Protect Protein and DNA against Stress-Induced Damage

Peroxiredoxins (Prxs) act against hydrogen peroxide (H(2)O(2)), organic peroxides, and peroxynitrite. Thermococcus kodakaraensis KOD1, an anaerobic archaeon, contains many antioxidant proteins, including three Prxs (Tk0537, Tk0815, and Tk1055). Only Tk0537 has been found to be induced in response to...

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Detalles Bibliográficos
Autores principales: Lee, Sangmin, Jia, Baolei, Liu, Jinliang, Pham, Bang Phuong, Kwak, Jae Myeong, Xuan, Yuan Hu, Cheong, Gang-Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416765/
https://www.ncbi.nlm.nih.gov/pubmed/25933432
http://dx.doi.org/10.1371/journal.pone.0125325