Copy Number Variation at the APOL1 Locus

Two coding variants in the APOL1 gene (G1 and G2) explain most of the high rate of kidney disease in African Americans. APOL1-associated kidney disease risk inheritance follows an autosomal recessive pattern: The relative risk of kidney disease associated with inheritance of two high-risk variants i...

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Detalles Bibliográficos
Autores principales: Ruchi, Rupam, Genovese, Giulio, Lee, Jessica, Charoonratana, Victoria T., Bernhardy, Andrea J., Alper, Seth L., Kopp, Jeffrey B., Thadhani, Ravi, Friedman, David J., Pollak, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416782/
https://www.ncbi.nlm.nih.gov/pubmed/25933006
http://dx.doi.org/10.1371/journal.pone.0125410

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416782/
https://www.ncbi.nlm.nih.gov/pubmed/25933006
http://dx.doi.org/10.1371/journal.pone.0125410

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