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Reed-Sternberg Cells Form by Abscission Failure in the Presence of Functional Aurora B Kinase

Large multinucleated Reed-Sternberg cells (RS) and large mononucleated Hodgkin cells (H) are traditionally considered to be the neoplastic population in classical Hodgkin lymphoma, (cHL) and postulated to promote the disease. However, the contribution of these larger cells to the progression of cHL...

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Detalles Bibliográficos
Autores principales: Xavier de Carvalho, Ana, Maiato, Helder, Maia, André F., Ribeiro, Susana A., Pontes, Patrícia, Bickmore, Wendy, Earnshaw, William C., Sambade, Clara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416800/
https://www.ncbi.nlm.nih.gov/pubmed/25933052
http://dx.doi.org/10.1371/journal.pone.0124629