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HIV Protease Inhibitors Sensitize Human Head and Neck Squamous Carcinoma Cells to Radiation by Activating Endoplasmic Reticulum Stress

BACKGROUND: Human head and neck squamous cell carcinoma (HNSCC) is the sixth most malignant cancer worldwide. Despite significant advances in the delivery of treatment and surgical reconstruction, there is no significant improvement of mortality rates for this disease in the past decades. Radiothera...

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Detalles Bibliográficos
Autores principales: Liu, Runping, Zhang, Luyong, Yang, Jing, Zhang, Xiaoxuan, Mikkelsen, Ross, Song, Shiyu, Zhou, Huiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416809/
https://www.ncbi.nlm.nih.gov/pubmed/25933118
http://dx.doi.org/10.1371/journal.pone.0125928