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Plasma Free Hemoglobin and Microcirculatory Response to Fresh or Old Blood Transfusions in Sepsis

BACKGROUND: Free hemoglobin (fHb) may induce vasoconstriction by scavenging nitric oxide. It may increase in older blood units due to storage lesions. This study evaluated whether old red blood cell transfusion increases plasma fHb in sepsis and how the microvascular response may be affected. METHOD...

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Detalles Bibliográficos
Autores principales: Damiani, Elisa, Adrario, Erica, Luchetti, Michele Maria, Scorcella, Claudia, Carsetti, Andrea, Mininno, Nicoletta, Pierantozzi, Silvia, Principi, Tiziana, Strovegli, Daniele, Bencivenga, Rosella, Gabrielli, Armando, Romano, Rocco, Pelaia, Paolo, Ince, Can, Donati, Abele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416810/
https://www.ncbi.nlm.nih.gov/pubmed/25932999
http://dx.doi.org/10.1371/journal.pone.0122655