P. falciparum and P. vivax Epitope-Focused VLPs Elicit Sterile Immunity to Blood Stage Infections

In order to design P. falciparum preerythrocytic vaccine candidates, a library of circumsporozoite (CS) T and B cell epitopes displayed on the woodchuck hepatitis virus core antigen (WHcAg) VLP platform was produced. To test the protective efficacy of the WHcAg-CS VLPs, hybrid CS P. berghei/P. falci...

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Detalles Bibliográficos
Autores principales: Whitacre, David C., Espinosa, Diego A., Peters, Cory J., Jones, Joyce E., Tucker, Amy E., Peterson, Darrell L., Zavala, Fidel P., Milich, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416889/
https://www.ncbi.nlm.nih.gov/pubmed/25933001
http://dx.doi.org/10.1371/journal.pone.0124856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416889/
https://www.ncbi.nlm.nih.gov/pubmed/25933001
http://dx.doi.org/10.1371/journal.pone.0124856

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