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An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor β (RARβ, NR1B2) Selective Agonist

Retinoic acid is an important regulator of cell differentiation which plays major roles in embryonic development and tissue remodeling. The biological action of retinoic acid is mediated by three nuclear receptors denoted RARα, β and γ. Multiple studies support that RARβ possesses functional charact...

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Detalles Bibliográficos
Autores principales: Nadendla, Eswarkumar, Teyssier, Catherine, Delfosse, Vanessa, Vivat, Valérie, Krishnasamy, Gunasekaran, Gronemeyer, Hinrich, Bourguet, William, Germain, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416907/
https://www.ncbi.nlm.nih.gov/pubmed/25933005
http://dx.doi.org/10.1371/journal.pone.0123195