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Incorporation of Porcine Adenovirus 4 Fiber Protein Enhances Infectivity of Adenovirus Vector on Dendritic Cells: Implications for Immune-Mediated Cancer Therapy

One strategy in cancer immunotherapy is to capitalize on the key immunoregulatory and antigen presenting capabilities of dendritic cells (DCs). This approach is dependent on efficient delivery of tumor specific antigens to DCs, which subsequently induce an anti-tumor T-cell mediated immune response....

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Detalles Bibliográficos
Autores principales: Wilkinson-Ryan, Ivy, Kim, Julius, Kim, Sojung, Ak, Ferhat, Dodson, Lindzy, Colonna, Marco, Powell, Matthew, Mutch, David, Spitzer, Dirk, Hansen, Ted, Goedegebuure, Simon P., Curiel, David, Hawkins, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416912/
https://www.ncbi.nlm.nih.gov/pubmed/25933160
http://dx.doi.org/10.1371/journal.pone.0125851