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OXPHOS-Mediated Induction of NAD(+) Promotes Complete Oxidation of Fatty Acids and Interdicts Non-Alcoholic Fatty Liver Disease

OXPHOS is believed to play an important role in non-alcoholic fatty liver disease (NAFLD), however, precise mechanisms whereby OXPHOS influences lipid homeostasis are incompletely understood. We previously reported that ectopic expression of LRPPRC, a protein that increases cristae density and OXPHO...

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Detalles Bibliográficos
Autores principales: Akie, Thomas E., Liu, Lijun, Nam, Minwoo, Lei, Shi, Cooper, Marcus P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416931/
https://www.ncbi.nlm.nih.gov/pubmed/25933096
http://dx.doi.org/10.1371/journal.pone.0125617