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Effective Treatment of Established GL261 Murine Gliomas through Picornavirus Vaccination-Enhanced Tumor Antigen-Specific CD8+ T Cell Responses

Glioblastoma (GBM) is among the most invasive and lethal of cancers, frequently infiltrating surrounding healthy tissue and giving rise to rapid recurrence. It is therefore critical to establish experimental model systems and develop therapeutic approaches that enhance anti-tumor immunity. In the cu...

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Detalles Bibliográficos
Autores principales: Renner, Danielle N., Jin, Fang, Litterman, Adam J., Balgeman, Alexis J., Hanson, Lisa M., Gamez, Jeffrey D., Chae, Michael, Carlson, Brett L., Sarkaria, Jann N., Parney, Ian F., Ohlfest, John R., Pirko, Istvan, Pavelko, Kevin D., Johnson, Aaron J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416934/
https://www.ncbi.nlm.nih.gov/pubmed/25933216
http://dx.doi.org/10.1371/journal.pone.0125565