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Global variability in gene expression and alternative splicing is modulated by mitochondrial content
Noise in gene expression is a main determinant of phenotypic variability. Increasing experimental evidence suggests that genome-wide cellular constraints largely contribute to the heterogeneity observed in gene products. It is still unclear, however, which global factors affect gene expression noise...
Autores principales: | Guantes, Raul, Rastrojo, Alberto, Neves, Ricardo, Lima, Ana, Aguado, Begoña, Iborra, Francisco J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417112/ https://www.ncbi.nlm.nih.gov/pubmed/25800673 http://dx.doi.org/10.1101/gr.178426.114 |
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