Organelle DNA rearrangement mapping reveals U-turn-like inversions as a major source of genomic instability in Arabidopsis and humans

Failure to maintain organelle genome stability has been linked to numerous phenotypes, including variegation and cytosolic male sterility (CMS) in plants, as well as cancer and neurodegenerative diseases in mammals. Here we describe a next-generation sequencing approach that precisely maps and chara...

Descripción completa

Detalles Bibliográficos
Autores principales: Zampini, Éric, Lepage, Étienne, Tremblay-Belzile, Samuel, Truche, Sébastien, Brisson, Normand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417113/
https://www.ncbi.nlm.nih.gov/pubmed/25800675
http://dx.doi.org/10.1101/gr.188573.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417113/
https://www.ncbi.nlm.nih.gov/pubmed/25800675
http://dx.doi.org/10.1101/gr.188573.114

Ejemplares similares