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Extensive microRNA-mediated crosstalk between lncRNAs and mRNAs in mouse embryonic stem cells

Recently, a handful of intergenic long noncoding RNAs (lncRNAs) have been shown to compete with mRNAs for binding to miRNAs and to contribute to development and disease. Beyond these reports, little is yet known of the extent and functional consequences of miRNA-mediated regulation of mRNA levels by...

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Detalles Bibliográficos
Autores principales: Tan, Jennifer Y., Sirey, Tamara, Honti, Frantisek, Graham, Bryony, Piovesan, Allison, Merkenschlager, Matthias, Webber, Caleb, Ponting, Chris P., Marques, Ana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417114/
https://www.ncbi.nlm.nih.gov/pubmed/25792609
http://dx.doi.org/10.1101/gr.181974.114