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Model-driven mapping of transcriptional networks reveals the circuitry and dynamics of virulence regulation

Key steps in understanding a biological process include identifying genes that are involved and determining how they are regulated. We developed a novel method for identifying transcription factors (TFs) involved in a specific process and used it to map regulation of the key virulence factor of a de...

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Detalles Bibliográficos
Autores principales: Maier, Ezekiel J., Haynes, Brian C., Gish, Stacey R., Wang, Zhuo A., Skowyra, Michael L., Marulli, Alyssa L., Doering, Tamara L., Brent, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417117/
https://www.ncbi.nlm.nih.gov/pubmed/25644834
http://dx.doi.org/10.1101/gr.184101.114