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A rapid and sensitive high-throughput screening method to identify compounds targeting protein–nucleic acids interactions
DNA-binding and RNA-binding proteins are usually considered ‘undruggable’ partly due to the lack of an efficient method to identify inhibitors from existing small molecule repositories. Here we report a rapid and sensitive high-throughput screening approach to identify compounds targeting protein–nu...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417145/ https://www.ncbi.nlm.nih.gov/pubmed/25653160 http://dx.doi.org/10.1093/nar/gkv069 |