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The hexameric structure of the human mitochondrial replicative helicase Twinkle

The mitochondrial replicative helicase Twinkle is involved in strand separation at the replication fork of mitochondrial DNA (mtDNA). Twinkle malfunction is associated with rare diseases that include late onset mitochondrial myopathies, neuromuscular disorders and fatal infantile mtDNA depletion syn...

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Detalles Bibliográficos
Autores principales: Fernández-Millán, Pablo, Lázaro, Melisa, Cansız-Arda, Şirin, Gerhold, Joachim M., Rajala, Nina, Schmitz, Claus-A., Silva-Espiña, Cristina, Gil, David, Bernadó, Pau, Valle, Mikel, Spelbrink, Johannes N., Solà, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417153/
https://www.ncbi.nlm.nih.gov/pubmed/25824949
http://dx.doi.org/10.1093/nar/gkv189