RBM7 subunit of the NEXT complex binds U-rich sequences and targets 3′-end extended forms of snRNAs

The Nuclear Exosome Targeting (NEXT) complex is a key cofactor of the mammalian nuclear exosome in the removal of Promoter Upstream Transcripts (PROMPTs) and potentially aberrant forms of other noncoding RNAs, such as snRNAs. NEXT is composed of three subunits SKIV2L2, ZCCHC8 and RBM7. We have recen...

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Detalles Bibliográficos
Autores principales: Hrossova, Dominika, Sikorsky, Tomas, Potesil, David, Bartosovic, Marek, Pasulka, Josef, Zdrahal, Zbynek, Stefl, Richard, Vanacova, Stepanka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417160/
https://www.ncbi.nlm.nih.gov/pubmed/25852104
http://dx.doi.org/10.1093/nar/gkv240

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417160/
https://www.ncbi.nlm.nih.gov/pubmed/25852104
http://dx.doi.org/10.1093/nar/gkv240

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