SubmiRine: assessing variants in microRNA targets using clinical genomic data sets

MicroRNAs (miRNAs) regulate gene expression by binding to partially complementary sequences on target mRNA transcripts, thereby causing their degradation, deadenylation, or inhibiting their translation. Genomic variants can alter miRNA regulation by modifying miRNA target sites, and multiple human d...

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Detalles Bibliográficos
Autores principales: Maxwell, Evan K., Campbell, Joshua D., Spira, Avrum, Baxevanis, Andreas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417167/
https://www.ncbi.nlm.nih.gov/pubmed/25813044
http://dx.doi.org/10.1093/nar/gkv256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4417167/
https://www.ncbi.nlm.nih.gov/pubmed/25813044
http://dx.doi.org/10.1093/nar/gkv256

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